Decarboxylative Organocatalyzed Addition Reactions of Fluoroacetate Surrogates for the Synthesis of Fluorinated Oxindoles.
DOI Number:
10.1021/acs.orglett.1c00172
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
2-fluoro-3-((4-methoxyphenyl)thio)-3-oxopropanoic acid, 4,7-dichloro-1-methylindoline-2,3-dione
Product:
S-(4-methoxyphenyl)-(R)-2-((R)-4,7-dichloro-3-hydroxy-1-methyl-2-oxoindolin-3-yl)-2-fluoroethanethioate
Catalyst:
N-(8α,9S)-cinchonan-9-yl-3,5-bis(trifluoromethyl)-benzenesulfonamide
Cas No:
1253690-78-6
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2