Enantioselective Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Ethyl Ester (Vinyl-ACCA-OEt) by Asymmetric Phase-Transfer Catalyzed Cyclopropanation of (E)-N-Phenylmethyleneglycine Ethyl Ester

DOI Number:

10.1021/op100070d

Reaction Category:

Educt:

(E)-N-(phenylmethylene)-glycine ethylester, trans-1,4-dibromo-2-butene

Product:

ethyl (1R,2S)-1-(((E)-benzylidene)amino)-2-vinylcyclopropane-1-carboxylate

Catalyst:

(8α,9R)1-[[2,4-Bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-cinchonanium bromide

Cas No:

1225330-70-0

Cas No:

485-71-2