Enantioselective Fluorination Mediated by N-Fluoroammonium Salts of Cinchona Alkaloids: First Enantioselective Synthesis of BMS-204352 (MaxiPost).
DOI Number:
10.1021/jo026792s
Reaction Category:
MOP ID:
MOP_0000597
Educt:
1-(tert-butyldimethylsilyl)-4-phenylbutan-1-one, trimethylsilanecarbonitrile
Product:
(S)-2-(tert-butyldimethylsilyl)-2-hydroxy-5-phenylpentanenitrile
Catalyst:
1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]oxy]-9,10-Anthracenedione
Cas No:
176097-24-8
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7