Binding Modes and Origins of Enantioselectivity in the Phase-Transfer-Catalyzed Conjugate Cyanation of β-Trifluoromethylated Chalcones.
DOI Number:
10.1021/acscatal.2c01904
Reaction Category:
MOP ID:
MOP_0000597
Educt:
beta-trifluoromethylated chalcones, 2-hydroxy-2-methylpropanenitrile
Product:
(R)-4-oxo-2,4-diphenyl-2-(trifluoromethyl)butanenitrile
Catalyst:
(9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide
Cas No:
1380297-63-1
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2