A general asymmetric copper-catalysed Sonogashira C (sp 3)–C (sp) coupling.

DOI Number:

10.1038/s41557-019-0346-2
Link to literature

Reaction Category:

Cross Coupling

Educt:

primary alkynes, organobromides

Product:

1,1,4-trisubstituted but-2-yne

Catalyst:

Copper(I) thiophene-2-carboxylate, 2-[Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzamide

Cas No:

2389028-68-4

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0