Practical Asymmetric Conjugate Alkynylation of Meldrum’s Acid-Derived Acceptors: Access to Chiral β-Alkynyl Acids.

DOI Number:

10.1021/ja909105s

Reaction Category:

Educt:

5-(substituted-methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione, (substituted-ethynyl)magnesium chloride

Product:

5-(1-substituted-3-substituted-prop-2-yn-1-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Catalyst:

Cinchonidine Base

Cas No:

485-71-2

Cas No:

485-71-2