Chlorosulfonamide salts are superior electrophilic chlorine precursors for the organocatalytic asymmetric chlorocyclization of unsaturated amides.

DOI Number:

10.1021/ol500861z
Link to literature

Reaction Category:

Chlorination | Cyclization | Cyclization | Further Cyclizations

MOP ID:

MOP_0000551

Educt:

substituted N-allylacetamide, chloramine-T

Product:

substituted (S)-5-chloro-5,6-dihydro-4H-1,3-oxazine

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7