Asymmetric chlorination/ring expansion for the synthesis of α-quaternary cycloalkanones.

DOI Number:

10.1021/ol5005565

Reaction Category:

MOP ID:

MOP_0000551

Educt:

substituted 1-(1-phenylvinyl)cyclobutan-1-ol, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione

Product:

substituted (S)-2-(chloromethyl)-2-phenylcyclopentan-1-one

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7