Asymmetric chlorocyclization of indole-3-yl-benzamides for the construction of fused indolines.

DOI Number:

10.1021/ol5007532
Link to literature

Reaction Category:

Chlorination | Cyclization | Cyclization | Further Cyclizations

MOP ID:

MOP_0000551

Educt:

indole-3-yl-benzamides, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione

Product:

(4aS,9aS)-4a-chloro-2-(m-tolyl)-9-tosyl-4,4a,9,9a-tetrahydro-[1,3]oxazino[6,5-b]indole

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7