Stereocontrolled construction of six vicinal stereogenic centers on a hexahydroxanthone framework through a formal [2+1+3] annulation.

DOI Number:

10.1039/C9CC08101A
Link to literature

Reaction Category:

Cascade reaction | Spirocyclization

Educt:

substituted tert-butyl (E)-2-(2-oxoindolin-3-ylidene)acetate, substituted 4-oxo-4H-chromene-3-carbaldehyde, nitromethane

Product:

spirocyclic compound

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0