Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and β-functionalized ketone.

DOI Number:

10.1039/C7RA08157J

Reaction Category:

Educt:

substituted phenols, malononitrile

Product:

2-amino-4H-chromene-3-carbonitriles

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0