Organocatalytic oxa/aza-Michael–Michael cascade strategy for the construction of spiro [chroman/tetrahydroquinoline-3, 3′-oxindole] scaffolds.

DOI Number:

10.1021/ol401595g
Link to literature

Reaction Category:

Cascade reaction | Spirocyclization

Educt:

substituted (E)-2-(2-oxoindolin-3-ylidene)acetate, substituted (E)-4-methyl-N-(2-(2-nitrovinyl)phenyl)benzenesulfonamide

Product:

spiro [chroman/tetrahydroquinoline-3, 3′-oxindole] scaffolds

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7