Organocatalytic oxa/aza-Michael–Michael cascade strategy for the construction of spiro [chroman/tetrahydroquinoline-3, 3′-oxindole] scaffolds.

DOI Number:

10.1021/ol401595g
Link to literature

Reaction Category:

Cascade reaction | Spirocyclization

Educt:

substituted (E)-2-(2-oxoindolin-3-ylidene)acetate, substituted (E)-2-(2-nitrovinyl)phenol

Product:

spiro [chroman/tetrahydroquinoline-3, 3′-oxindole] scaffolds

Catalyst:

3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1210360-60-3

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0