Enantioselective synthesis of benzoindolizidine derivatives using chiral phase-transfer catalytic intramolecular domino aza-Michael addition/alkylation.
DOI Number:
10.1039/c4ob02227k
Reaction Category:
Educt:
(E)-N-(4-bromo-2-(3-oxo-3-phenylprop-1-en-1-yl)phenethyl)-2-chloroacetamide
Product:
(1R,10bR)-1-benzoyl-9-bromo-1,5,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-3(2H)-one
Catalyst:
(8α,9R)-(8′′α,9′′R)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-Cinchonanium chloride (1:2)
Cas No:
462128-11-6
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2