Diastereodivergent Synthesis of Bridged Tetrahydroisoquinoline Derivatives Catalyzed by Modularly Designed Organocatalysts.

DOI Number:

10.1002/adsc.202000227

Reaction Category:

MOP ID:

MOP_0000561

Educt:

(E)-2-(2-(3-oxo-3-phenylprop-1-en-1-yl)phenyl)acetaldehyde, Ethyl (2E)-2-[(4-methoxyphenyl)imino]acetate

Product:

bridged tetrahydroisoquinoline derivatives

Catalyst:

D-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8