Organocatalytic sulfa-Michael/aldol cascade: constructing functionalized 2,5-dihydrothiophenes bearing a quaternary carbon stereocenter.

DOI Number:

10.1039/c8ra04325f

Reaction Category:

Educt:

diethyl 2,5-dihydroxy-1,4-dithiane-2,5-dicarboxylate, tert-butyl (Z)-3-nitro-2-phenylacrylate

Product:

2-(tert-butyl) 4-ethyl (S)-3-nitro-2-phenyl-2,5-dihydrothiophene-2,4-dicarboxylate

Catalyst:

3-[(3,5-dimethylphenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1372409-38-5

Cas No:

130-95-0