Enantioselective sequential Michael addition/C-H olefination/Michael reaction for the efficient collective synthesis of clavine alkaloids.
DOI Number:
10.1016/j.xcrp.2024.102112
Reaction Category:
Educt:
2-phenyl-N-(quinolin-8-yl)acrylamide, nitromethane, methyl (E)-3-iodoacrylate
Product:
methyl 2-((1R,2R,4R)-2-nitro-4-(quinolin-8-ylcarbamoyl)-1,2,3,4-tetrahydronaphthalen-1-yl)acetate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7