Enantioselective, desymmetrizing bromolactonization of alkynes.

DOI Number:

10.1021/ja402910d
Link to literature

Reaction Category:

Bromination | Desymmetrization | Lactonization

MOP ID:

MOP_0000551

Educt:

alkynes, N-bromsuccinimid

Product:

substituted (R,E)-5-(bromomethylene)-3-(prop-2-yn-1-yl)dihydrofuran-2(3H)-one

Catalyst:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7