Diastereoselective aziridination of chiral electron-deficient olefins with N-chloro-N-sodiocarbamates catalyzed by chiral quaternary ammonium salts.

DOI Number:

10.1021/jo2010632
Link to literature

Reaction Category:

Aziridination

Educt:

1-((4R,7S)-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazol-1-yl)prop-2-en-1-one, N-chloro-N-sodiocarbamates

Product:

benzyl (S)-2-((4R,7S)-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole-1-carbonyl)aziridine-1-carboxylate

Catalyst:

1-(9-anthracenylmethyl)-9-(2-propenyloxy)-(8α,9R)-cinchonanium bromide

Cas No:

200132-54-3

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2