Asymmetric catalyzed intramolecular aza-Michael reaction mediated by quinine-derived primary amines.

DOI Number:

10.1016/j.cclet.2017.04.017
Link to literature

Reaction Category:

Aza-Michael | Intramolecular Aza-Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

tert-butyl (E)-(2-((4-oxopent-2-en-1-yl)oxy)ethyl)carbamate

Product:

tert-butyl (S)-3-(2-oxopropyl)morpholine-4-carboxylate

Catalyst:

diphenyl hydrogenphosphate, (8α,9S)-6′-Methoxycinchonan-9-amine

Cas No:

168960-95-0

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0