Asymmetric synthesis of fluoroalkylated N,O-ketals via an organocatalytic dehydration/aminalization/aza-Michael desymmetrization.
DOI Number:
10.1039/C8QO01397G
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
substituted 3-hydroxy-3-(trifluoromethyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, substituted 4-hydroxycyclohexa-2,5-dien-1-one
Product:
fluoroalkylated N,O-ketals
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7