Organocatalytic Enantioselective 1,6-aza-Michael Addition of Isoxazolin-5-ones to p-Quinone Methides.
DOI Number:
10.1002/ejoc.201901907
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
3-methylisoxazol-5(4H)-one, 2,6-di-tert-butyl-4-(2-chlorobenzylidene)cyclohexa-2,5-dien-1-one
Product:
(R)-2-((2-chlorophenyl)(3,5-di-tert-butyl-4-hydroxyphenyl)methyl)-3-methylisoxazol-5(2H)-one
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0