Cinchona alkaloid derivatives catalyzed asymmetric aza‐Friedel–crafts reaction of α‐naphthols with aryl aldimines.
![](https://www.buchler-gmbh.com/wp-content/uploads/Aza-Friedel-Crafts-3.jpg)
DOI Number:
10.1002/chir.22714
Reaction Category:
RXNO ID:
RXNO_0000369
Educt:
1-Naphthol, 4-Methyl-N-[[2-(trifluoromethyl)phenyl]methylene]benzenesulfonamide
Product:
N-[(R)-(1-Hydroxy-2-naphthalenyl)[2-(trifluoromethyl)phenyl]methyl]-4-methylbenzenesulfonamide
Catalyst:
4-((R)-((tert-butyldiphenylsilyl)oxy)((1S,2S,4S,5R)- 5-vinylquinuclidin-2-yl)methyl)quinolin-6-ol
Cas No:
Associated Product from Buchler GmbH:
Cupreine Base
Cas No:
524-63-0