Enantioselective Inverse-Electron Demand Aza-Diels–Alder Reaction: ipso, α-Selectivity of Silyl Dienol Ethers.

DOI Number:

10.1021/acscatal.1c03390

Reaction Category:

RXNO ID:

RXNO_0000006

Educt:

N-((E)-2-((Z)-3-methoxybenzylidene)benzofuran-3(2H)-ylidene)-4-methylbenzenesulfonamide, trimethyl(styryloxy)silane

Product:

(2R,3S,4S)-4-(3-methoxyphenyl)-3-phenyl-1-tosyl-1,2,3,4-tetrahydrobenzofuro[3,2-b]pyridin-2-ol

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione

Cas No:

1335030-68-6

Cas No:

485-71-2