Enantioselective synthesis of chiral amides by carbene insertion into amide N–H bond.

DOI Number:

10.1038/s41467-024-48266-5
Link to literature

Reaction Category:

alpha-Amination | Amination

Educt:

amides, α-diazoketones

Product:

chiral amides

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea

Cas No:

852913-19-0

Associated Product from Buchler GmbH:

Dihydroquinine Base

Cas No:

522-66-7