Highly enantioselective γ-amination of α,β-unsaturated acyl chlorides with azodicarboxylates: efficient synthesis of chiral γ-amino acid derivatives.

DOI Number:

10.1021/ja206819y

Reaction Category:

Educt:

α,β-unsaturated acyl chlorides, azodicarboxylates

Product:

di-tert-butyl (S)-3-oxo-3,5,6,7,8,8a-hexahydrocinnoline-1,2-dicarboxylate

Catalyst:

(9S)-6′-methoxy-9-[(trimethylsilyl)oxy]-cinchonan hydrochloride

Cas No:

931581-06-5

Cas No:

56-54-2