Stereoselective α-Chlorination of β-Keto Esters in the Presence of Hybrid Amide-Based Cinchona Alkaloids as Catalysts.

DOI Number:

10.1021/acs.joc.0c02486
Link to literature

Reaction Category:

Chlorination

MOP ID:

MOP_0000551

Educt:

methyl 4-bromo-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, Chlorosuccinimide

Product:

methyl (R)-4-bromo-2-chloro-1-oxo-2,3-dihydro-1H-indene-2-carboxylate

Catalyst:

1-[2-([1,1′-biphenyl]-2-ylamino)-2-oxoethyl]-9-hydroxy-6′-methoxy-(8α,9R)-Cinchonanium bromide (1:1)

Cas No:

2581996-67-8

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0