Highly Enantioselective Synthesis of α-Alkyl-alanines via the Catalytic Phase-Transfer Alkylation of 2-Naphthyl Aldimine tert-Butyl Ester by Using O(9)-Allyl-N(1)-2‘,3‘,4‘-trifluorobenzylhydrocinchonidinium Bromide.
DOI Number:
10.1021/jo034006t
Reaction Category:
MOP ID:
MOP_0000369
Educt:
tert-butyl (E)-2-((arylmethylene)amino)propanoate, (bromomethyl)benzene
Product:
tert-butyl (R,E)-2-((arylmethylene)amino)-2-methyl-3-phenylpropanoate
Catalyst:
(8α,9R)-10,11-dihydro-9-(2-propen-1-yloxy)-1-[(2,3,4-trifluorophenyl)methyl]-Cinchonanium bromide
Cas No:
479617-92-0
Associated Product from Buchler GmbH:
Dihydrocinchonidine Base
Cas No:
485-64-3