Asymmetric syntheses of spiro-oxindole compounds that may be useful as therapeutic agents.

DOI Number:

Patent WO2013154712A1

Reaction Category:

MOP ID:

MOP_0000369

Educt:

2-butyl-4-chloro-6-fluoro-5-methoxy-2,3-dihydro-1H-inden-1-one, 1,3-dichlorobut-2-ene

Product:

(S,Z)-4-chloro-2-(3-chlorobut-2-en-1-yl)-6-fluoro-5-methoxy-2-pentyl-2,3-dihydro-1H-inden-1-one

Catalyst:

9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-cinchonanium bromide

Cas No:

95088-20-3

Cas No:

118-10-5