Organocatalytic enantioselective nucleophilic vinylic substitution by α-substituted-α-cyanoacetates under phase-transfer conditions.

DOI Number:

10.1021/jo070024p

Reaction Category:

MOP ID:

MOP_0000369

Educt:

substituted (Z)-4-chlorobut-3-en-2-one, alpha-substituted-alpha-cyanoacetates

Product:

substituted tert-butyl (R,Z)-2-cyano-5-oxohex-3-enoate

Catalyst:

(9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[10,11-dihydro-9-(2-propen-1-yloxy)-cinchonanium dibromide

Cas No:

936484-54-7

Cas No:

485-65-4