Synthesis of chiral α-trifluoromethylamines with 2,2,2-trifluoroethylamine as a “Building Block”.
DOI Number:
10.1021/acs.orglett.5b03566
Reaction Category:
MOP ID:
MOP_0000369
Educt:
N-2,2,2-trifluoroethylisatin ketimines, MBH carbonates
Product:
substituted (S,E)-5,5,5-trifluoro-4-((1-methyl-2-oxoindolin-3-ylidene)amino)-2-methylenepentanal
Catalyst:
(3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan-6′-ol
Cas No:
253430-48-7
Associated Product from Buchler GmbH:
Dihydrocupreidine Base
Cas No:
73522-75-5