Enantioselective decarboxylative aldol addition of β-ketoacids to isatins catalyzed by binaphthyl-modified organocatalyst.
DOI Number:
10.1016/j.tetlet.2013.04.132
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
3-(4-fluorophenyl)-3-oxopropanoic acid, tert-butyl 2,3-dioxoindoline-1-carboxylate
Product:
tert-butyl (R)-3-(2-(4-fluorophenyl)-2-oxoethyl)-3-hydroxy-2-oxoindoline-1-carboxylate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea
Cas No:
890044-38-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2