Asymmetric Michael and aldol addition using bifunctional Cinchona alkaloid based catalysts.

DOI Number:

Patent WO2005121137
Link to literature

Reaction Category:

Aldol | Henry | Henry | Nitroaldol

RXNO ID:

RXNO_0000086

Educt:

2-substituted ethyl 2-oxoacetate, nitromethane

Product:

2-substituted ethyl 2-hydroxy-3-nitropropanoate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0