Rational combination of two privileged chiral backbones: Highly efficient organocatalysts for asymmetric direct aldol reactions between aromatic aldehydes and acylic ketones.

DOI Number:

10.1021/jo800910s
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

2-nitrobenzaldehyde, acetone

Product:

4-hydroxy-4-(2-nitrophenyl)butan-2-one

Catalyst:

(2S)-N-(8α,9S)-cinchonan-9-yl-2-Pyrrolidinecarboxamide

Cas No:

1040729-03-0

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2