Organocatalytic Asymmetric Direct Aldol Reaction of Pyruvic Aldehyde Dimethyl Acetal with Isatin Derivatives.

DOI Number:

10.1002/ejoc.201300411
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

1,5,7-trisubstituted indoline-2,3-dione, 1,1-dimethoxypropan-2-one

Product:

(S)-1,5,7-trisubstituted- 3-(3,3-dimethoxy-2-oxopropyl)-3-hydroxyindolin-2-one

Catalyst:

(9R)-Cinchonan-9-amine

Cas No:

168960-96-1

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5