Biomimetic catalytic enantioselective decarboxylative aldol reaction of β-ketoacids with trifluoromethyl ketones.

DOI Number:

10.1039/C2CC30949A
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

β-ketoacids, trifluoromethyl ketones

Product:

(R)-4,4,4-trifluoro-3-hydroxy-1,3-diphenylbutan-1-one

Catalyst:

1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione

Cas No:

176298-44-5

Associated Product from Buchler GmbH:

Dihydroquinidine Base

Cas No:

1435-55-8