Asymmetric aldol addition of α-azido ketones to ethyl pyruvate mediated by a cinchona-based bifunctional urea catalyst.

DOI Number:

10.1016/j.tetlet.2014.06.018
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

α-azido ketones, ethyl pyruvate

Product:

substituted ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-phenylbutanoate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea

Cas No:

957770-66-0

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0