Enantioselective 1,4-addition of kojic acid derivatives to β-nitroolefins catalyzed by a cinchonine derived sugar thiourea.

DOI Number:

10.1039/C3RA47423B

Reaction Category:

Educt:

kojic acid derivatives, β-nitroolefins

Product:

6-(((tert-butyldimethylsilyl)oxy)methyl)-3-hydroxy-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one

Catalyst:

(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Cas No:

56-54-2