Enantioselective Amine-Catalyzed [4+ 2] Annulations of Allene Ketones and 2,3-Dioxopyrrolidine Derivatives: Synthesis of 4 H-Pyran Derivatives.

DOI Number:

10.1021/acs.joc.5b00961
Link to literature

Reaction Category:

[4+2]-Cycloaddition | Cyclization

MOP ID:

MOP_0000565

Educt:

2,3-dioxopyrrolidine derivatives, allene ketones

Product:

(R)-6-benzyl-4-(3-bromophenyl)-2-(2-oxo-2-phenylethyl)-5,6-dihydropyrano[2,3-c]pyrrol-7(4H)-one

Catalyst:

6′-methoxy-(9S)-Cinchonan-9-ol-9-benzoate

Cas No:

60723-45-7

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2