Diastereodivergent construction of bispiro[oxindole-bipyrrolidine]s with four consecutive stereocenters via asymmetric [3+2]-cycloaddition of 2,3-dioxopyrrolidines using identical catalysts.

DOI Number:

10.1039/C9QO00452A

Reaction Category:

MOP ID:

MOP_0000715

Educt:

2,3-dioxopyrrolidines, N-2,2,2-trifluoroethylisatin ketimines

Product:

bispiro[oxindole-bipyrrolidine]s

Catalyst:

3-[[4-(1,1-dimethylethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

2241925-42-6

Cas No:

130-95-0