Quinidine-catalyzed enantioselective domino Michael addition/cyclization process: Synthesis of chiral 1, 4-dihydro-pyridine containing benzosultams.

DOI Number:

10.1016/j.mcat.2022.112165

Reaction Category:

MOP ID:

MOP_0000561

Educt:

substituted (E)-3-(prop-1-en-1-yl)benzo[d]isothiazole 1,1-dioxide, malononitrile

Product:

(9S)-substituted 7-amino--9H-benzo[4,5]isothiazolo[2,3-a]pyridine-8-carbonitrile 5,5-dioxide

Catalyst:

Quinidine Base

Cas No:

56-54-2

Cas No:

56-54-2