Double thiol-chiral Brønsted base catalysis: asymmetric cross Rauhut–Currier reaction and sequential [4+ 2] annulation for assembly of different activated olefins.
DOI Number:
10.1021/acs.orglett.9b02944
Reaction Category:
Educt:
N/C-substituted 2-(2-oxoindolin-3-ylidene)malononitrile, cyclopent-2-en-1-one
Product:
N/C-substituted (S)-2-(2-oxo-3-(5-oxocyclopent-1-en-1-yl)indolin-3-yl)malononitrile
Catalyst:
2-mercaptobenzoic acid, (9S)-9-hydroxy-1-(phenylmethyl)-cinchonanium bromide
Cas No:
85653-34-5
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5