Asymmetric bromolactonization using amino-thiocarbamate catalyst.

DOI Number:

10.1021/ja1048972
Link to literature

Reaction Category:

Bromination | Cyclization | Further Cyclizations | Intramolecular cyclization | Lactonization

MOP ID:

MOP_0000551

Educt:

4-substituted pent-4-enoic acid, N-bromosuccinimide

Product:

5-substituted (R)-5-(bromomethyl)-dihydrofuran-2(3H)-one

Catalyst:

(9S)-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol

Cas No:

1254701-61-5

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5