Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction.

DOI Number:

10.1039/C1SC00592H
Link to literature

Reaction Category:

Cascade reaction | Cyclization

MOP ID:

MOP_0000561

Educt:

(E)-1-methyl-4-(2-nitrovinyl)benzene, ethyl (E)-6-nitrohex-2-enoate

Product:

ethyl 2-((1S,2R,3R,4S)-2,4-dinitro-3-(p-tolyl)cyclohexyl)acetate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)- 6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7