Cinchonamine Squaramide Catalyzed Asymmetric aza-Michael Reaction: Dihydroisoquinolines and Tetrahydropyridines.

DOI Number:

10.1002/anie.201805020

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

(E)-3-(2-(2-oxopropyl)phenyl)-1-phenylprop-2-en-1-one, 4-methylbenzenesulfonamide

Product:

(R)-1-phenyl-2-(2-tosyl-1,2-dihydroisoquinolin-1-yl)ethan-1-one

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0