C60 steric bulk of cinchona alkaloid enables an enantioselective Michael addition/annulation sequence toward pyranopyrazoles.
DOI Number:
10.1039/c8cc00154e
Reaction Category:
MOP ID:
MOP_0000561
Educt:
2-(phenylethynyl)cyclohex-2-en-1-one, 2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one
Product:
(S)-5-benzyl-1,3-diphenyl-7,8,9,9a-tetrahydroisochromeno[3,4-c]pyrazol-6(3H)-one
Catalyst:
(8α,9R)-6′-[[Tris(1-methylethyl)silyl]oxy]cinchonan-9-ol
Cas No:
876269-53-3
Associated Product from Buchler GmbH:
Cupreine Base
Cas No:
524-63-0