Chiral Bifunctional Amine-Squaramide-Catalyzed Highly Diastereo- and Enantioselective Michael/Aldol Cascade Reaction of 2-Mercaptobenzaldehyde and α,β-Unsaturated 7-Azaindoline Amides.
DOI Number:
10.1021/acs.joc.9b00837
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
alpha,beta unsaturated 7-azaindoline amide, 2-mercaptobenzaldehyde
Product:
thiochromans
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione
Cas No:
1256245-86-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2