Enantioselective Fluorination Mediated by Cinchona Alkaloid Derivatives/Selectfluor Combinations: Reaction Scope and Structural Information for N-Fluorocinchona Alkaloids.
![](https://www.buchler-gmbh.com/wp-content/uploads/alpha-fluorination-of-carbonyl-compounds.jpg)
DOI Number:
10.1021/ja010789t
Reaction Category:
MOP ID:
MOP_0000553
Educt:
((2-benzyl-1H-inden-3-yl)oxy)trimethylsilane, 1-(chloromethyl)-4-fluoro-1,4-Diazoniabicyclo[2.2.2]octane tetrafluoroborate
Product:
(R)-2-benzyl-2-fluoro-2,3-dihydro-1H-inden-1-one
Catalyst:
(R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl 4-chlorobenzoate
Cas No:
113216-88-9
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7