Heteroannulation, dinaphtho[2,1-b:1′,2′-d]furan-2-ol, (Z)-1-(2-chloro-2-nitrovinyl)-4-(trifluoromethyl)benzene, dioxa[6]helicenes, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(phenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCyclization, Further Cyclizations, Heteroannulation Mannich reaction, 4-methoxy-6-methylpyrimidin-2-amine, malonic acid esters, aldehydes, amino-pyrimidine derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich [4+2]-Cycloaddition, vinylidene ortho-quinone methides, benzofurans, oxygen-containing [5-6-5] tricyclic heterocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[4+2]-Cycloaddition, Cyclization, Cycloaddition Aldol reaction, 2-nitrobenzaldehyde, acetone, 4-hydroxy-4-(2-nitrophenyl)butan-2-one, (2S)-N-(8α,9S)-cinchonan-9-yl-2-Pyrrolidinecarboxamide, Cinchonidine DerivativeAldol, Aldol Pictet-Spengler, methyl 2,2-dimethoxy-5-oxopentanoate, substituted 2-(1H-indol-3-yl)ethan-1-amine, substituted methyl 2,2-dimethoxy-4-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction Mannich reaction, isatin derived N-boc ketimines, 1,3-diketones, 3-amino-oxindoles, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich Michael Addition, 1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, 2-chloroacrylonitrile, (S)-2-((S)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, (R)-2-((S)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Biginelli reaction, aldehydes, thiourea, 4-methyl-3-oxopentanoic acid esters, 6-isopropyl-3,4-dihydropyrimidines, (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeBiginelli reaction, Further reactions Michael Addition, (E)-nitro olefins, ketones, carbamates, tetrahydroacridines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition 1,3-dipolar Cycloaddition, (Z)-2,4-Dihydro-5-methyl-2-phenyl-4-(phenylmethylene)-3H-pyrazol-3-one, (E)-Dihydro-3-[(2-thienylmethylene)amino]-2(3H)-furanone, (5S,6R,7R,13R)-4-Methyl-2,6-diphenyl-13-(2-thienyl)-9-oxa-2,3,12-triazadispiro[4.1.4.2]tridec-3-ene-1,8-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative1,3-Dipolar Cycloaddition, Cycloaddition, Spirocyclization« Older Entries
Heteroannulation, dinaphtho[2,1-b:1′,2′-d]furan-2-ol, (Z)-1-(2-chloro-2-nitrovinyl)-4-(trifluoromethyl)benzene, dioxa[6]helicenes, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[(phenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCyclization, Further Cyclizations, Heteroannulation
Mannich reaction, 4-methoxy-6-methylpyrimidin-2-amine, malonic acid esters, aldehydes, amino-pyrimidine derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
[4+2]-Cycloaddition, vinylidene ortho-quinone methides, benzofurans, oxygen-containing [5-6-5] tricyclic heterocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[4+2]-Cycloaddition, Cyclization, Cycloaddition
Aldol reaction, 2-nitrobenzaldehyde, acetone, 4-hydroxy-4-(2-nitrophenyl)butan-2-one, (2S)-N-(8α,9S)-cinchonan-9-yl-2-Pyrrolidinecarboxamide, Cinchonidine DerivativeAldol, Aldol
Pictet-Spengler, methyl 2,2-dimethoxy-5-oxopentanoate, substituted 2-(1H-indol-3-yl)ethan-1-amine, substituted methyl 2,2-dimethoxy-4-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction
Mannich reaction, isatin derived N-boc ketimines, 1,3-diketones, 3-amino-oxindoles, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
Michael Addition, 1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, 2-chloroacrylonitrile, (S)-2-((S)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, (R)-2-((S)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Biginelli reaction, aldehydes, thiourea, 4-methyl-3-oxopentanoic acid esters, 6-isopropyl-3,4-dihydropyrimidines, (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeBiginelli reaction, Further reactions
Michael Addition, (E)-nitro olefins, ketones, carbamates, tetrahydroacridines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
1,3-dipolar Cycloaddition, (Z)-2,4-Dihydro-5-methyl-2-phenyl-4-(phenylmethylene)-3H-pyrazol-3-one, (E)-Dihydro-3-[(2-thienylmethylene)amino]-2(3H)-furanone, (5S,6R,7R,13R)-4-Methyl-2,6-diphenyl-13-(2-thienyl)-9-oxa-2,3,12-triazadispiro[4.1.4.2]tridec-3-ene-1,8-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative1,3-Dipolar Cycloaddition, Cycloaddition, Spirocyclization
