Direct asymmetric Michael addition of phthalide derivatives to chalcones.

DOI Number:

10.1016/j.tetlet.2013.07.108
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

phthalide derivatives, chalcones

Product:

substituted tert-butyl (R)-3-oxo-1-(3-oxo-3-substituted-propyl)-1,3-dihydroisobenzofuran-1-carboxylate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7